Ashwagandha (Withania somnifera), also known as Indian ginseng, is a traditional herb used in Ayurvedic medicine. It is classified as a Rasayana (rejuvenating tonic) and is commonly described as an adaptogen—a substance that helps support the body's response to mental and physical stress.
Over the past decade, research on Ashwagandha has grown substantially. This expanding body of evidence builds on its long history of traditional use and provides increasing scientific support for many of its established applications.
Ashwagandha's physiological effects are owed to Withanolides. Evidence suggests that Withanolides may affect the hypothalamic-pituitary-adrenal axis. A recent 2025 Ashwagandha review, 'Withania somnifera (Ashwagandha) supplementation: a review of its mechanisms, health benefits, and role in sports performance', shows the majority of Ashwgandha's effects are the following:
- Reliable reduction in stress
- Reliably reducing anxiety and fatigue associated with stress
Further, there is some preliminary evidence on power output and VO2 Max, but requires further research.
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Root vs. Leaf — Why It Matters
Absorb Science's Ashwagandha Extract is derived exclusively from the root of Withania somnifera.
Ashwagandha root naturally contains higher concentrations of the withanolides most commonly studied in human clinical research, while the leaves contain greater amounts of withaferin A. Although withaferin A is an active compound, its potential health effects require further investigation and are not believed to be the same as Withanolides.
How Ashwagandha Works
Ashwagandha contains naturally occurring active compounds known as Withanolides. These compounds are believed to contribute to the herb’s adaptogenic properties and its ability to support the body’s response to stress.
By supporting a balanced stress response, Ashwagandha may help promote a sense of calm without reducing normal daytime energy.
Recommended Dose
Adults: Take according to the directions provided on the product label.
NPN:80149100


